Salaries & JobsUpdated March 2026

Registered Nurse Salary in Des Moines, IA

Average annual salary for registered nurses. Data sourced from BLS, U.S. Census Bureau, and industry surveys.

Avg Salary
$47,160
37% below avg
Cost Range
$34,584 – $59,736
National Avg
$75,000
State Avg
$52,762
Cost Index
89/100
YoY Trend
+2.3%
Growing
Reviewed by Thomas Nguyen, Wage & Benefits Economist|Last verified: March 2026|Sources: BLS, Census Bureau, HUD
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Average Registered Nurse Salary in Des Moines

Living in Des Moines means navigating a housing market where the American Dream of owning a home is still financially realistic and lake houses, state fairs, and a quality of life that coastal transplants often describe as 'the secret nobody talks about.' When it comes to registered nurse salary, that translates to costs that comes at a significant discount compared to national averages, running 37% cheaper. The typical resident here pays between $34,584 and $59,736, compared to a national average of $75,000.

Average Annual Salary Range
$34,584$59,736
-37% vs national average
$34,584$47,160$59,736
LowNational avg: $75,000High

What Affects Registered Nurse Salary Pay in Des Moines?

Des Moines is a community where the same service costs 30% more downtown than ten minutes out in the suburbs. The housing landscape here features a housing market where the American Dream of owning a home is still financially realistic. The local workforce for registered nurse salary reflects a price-competitive market where local businesses work harder for each customer. And the midwestern climate shapes demand in predictable ways: severe storms, including tornadoes in some areas, make insurance a more significant budget item than most newcomers expect.

What Matters Most

Nursing specialty, shift differential, and facility type create a wider range than most people expect. ICU and OR nurses earn 15-25% more than general floor nurses; night shift adds another 10-15%.

Pro Tip

Travel nursing contracts still offer $10,000-20,000 more per 13-week assignment than permanent positions. Even one or two travel stints per year can significantly boost annual income.

Common Mistake

Comparing salaries without factoring in benefits. Hospital-employed nurses typically receive health insurance, pension contributions, and tuition reimbursement worth $10,000-20,000/year beyond base pay.

Best Time to Buy

Flu season (October-March) and summer vacation coverage create the highest demand for per diem and travel nurses. Rates during these windows are 20-40% above baseline.

Registered Nurse Salary Pay: Des Moines vs State & National Average

CategoryDes MoinesIowa AvgNational Avg
Average salary$47,160$52,762$75,000
Low estimate$34,584$39,572$56,250
High estimate$59,736$68,591$97,500

Take Action on This Data

Registered Nurse Salary in Des Moines: $34,584 – $59,736 (national avg: $75,000)

💼 Compare Salaries💰 Can I Afford It?

Negotiation Leverage

Registered Nurse professionals in Des Moines face the 'costs are low here' challenge. Counter with: remote alternatives, skills scarcity, and total compensation. The most effective tactic: have a competing offer.

Purchasing Power

$47,160 in Des Moines has real purchasing power of ~$52,989 at national baseline. Your salary goes 37% further here than in an average-cost city.

Year-over-Year Trend

+2.3%
GrowingRegistered Nurse Salary pay in Des Moines

Registered Nurse Salary in Des Moines increased 2.3% year-over-year, slightly above the national average.

Registered Nurse Salary by Experience Level in Des Moines

Registered Nurse Salary in Des Moines

Adjusted for Des Moines
13 compensation levels — hover rows for details
Level / RoleLowHighNote
CNA (Certified Nursing Assistant)
$17,606$25,152
LPN / LVN (Licensed Practical Nurse)
$25,152$34,584
RN — Staff Nurse (hospital)
$34,584$53,448
RN — Specialty (ICU, ER, OR)
$40,872$59,736
RN — Outpatient / clinic
$31,440$47,160
Travel nurse (13-week contract)
$44,016$75,456annualized + housing
Nurse Practitioner (NP)
$56,592$81,744
CRNA (Nurse Anesthetist)
$94,320$138,336highest-paid nursing
Clinical Nurse Specialist
$47,160$69,168
Nurse Manager / Director
$50,304$75,456
Per diem / PRN rate
$30$60per hour
Overtime rate (time and a half)
$40$75per hour
Sign-on bonus (high-demand areas)
$3,144$12,576one-time
13 items listed · Annual figuresData verified March 2026

Is Des Moines Cheap or Expensive for Registered Nurse Salary?

Compensation for registered nurses in Des Moines is shaped by local employer demand, cost of living (index: 89), and the midwestern labor market. Moderate costs mean employers face less pressure to inflate salaries, but they also don't need to — your dollars go further.

Practical Advice for Des Moines

💡 Des Moines offers a balanced job market: enough employers to ensure competitive pay, without the extreme cost-of-living that erodes purchasing power in top-10 metros. Remote roles headquartered elsewhere can boost your effective compensation significantly.

Smart Career Moves

  • Understand the 401(k) match structure: a 6% match on $80K = $4,800/year
  • Research typical benefits packages for your industry in this market
  • Ask about remote/hybrid flexibility — it may affect compensation
  • Look at the employer's health insurance contribution — it varies by $2,000-8,000/year
  • Research salary ranges on Glassdoor, Levels.fyi, and BLS for your specific role
  • Research career advancement timelines at target employers

How to Maximize Registered Nurse Earnings in Des Moines

1

Factor in IA state income tax when comparing offers across states — the difference can shift your effective pay by $3,000-9,000 per year.

2

Use cost-of-living calculators to present your case when negotiating remote compensation. Showing your employer the data strengthens requests for location-adjusted pay.

3

Remote work lets you earn higher-market salaries while enjoying Des Moines's cost of living. Target companies headquartered in high-cost metros.

4

Des Moines's job market rewards mobility. Employees who switch employers every 2-3 years typically see 10-20% salary increases versus 3-4% for those who stay put.

Hidden Costs of Registered Nurse Salary in Des Moines That Most People Miss

The salary figure for registered nurse salary in Des Moines is just the starting point of your compensation story. After IA state income tax, federal tax, FICA, and benefit deductions, your take-home pay is typically 65-75% of your gross salary. In Des Moines, that translates to roughly $33,012 to $35,370 annually in actual spendable income.

Beyond raw pay, total compensation in Des Moines varies dramatically by employer. Health insurance contributions alone differ by $3,000-$8,000 per year between employers. A 401(k) match of 4-6% on a $47K salary adds $2K in free money annually. Remote work stipends, professional development budgets, and equity compensation can add another 10-25% to your effective pay — but only if you know to negotiate for them.

The hidden cost of career advancement in Des Moines: commute expenses ($267-$623/month including gas, parking, or transit), professional wardrobe, networking events, continuing education, and the stress premium of high-cost-of-living markets. When evaluating registered nurse salary offers in Des Moines, model the full picture — not just the number on the offer letter.

How Des Moines Compares Regionally for Registered Nurse Salary

Regionally, Des Moines occupies a value-oriented position for registered nurse salary costs. Compared to nearby Cedar Rapids, Omaha, St. Joseph, Des Moines's pricing reflects its unique economic profile: a mid-size city balancing accessibility with quality. The midwest region generally provides moderate pricing with seasonal variability. Your decision should factor in not just the raw cost, but the value equation: what you get for what you pay, including response times, quality standards, and available options.

Registered Nurse Salary by Career Stage in Des Moines

Early Career (0-3 years)

$29,396 – $42,444/year

Entry-level registered nurse in Des Moines

Focus on skill development over salary optimization. Your purchasing power here is strong — invest the savings difference.

Mid-Career (4-8 years)

$44,802 – $53,762/year

Experienced registered nurse with specialized skills

This is your highest-leverage negotiation window. Multiple offers and demonstrated impact justify 15-25% above market midpoint in Des Moines.

Senior (8+ years)

$51,876 – $68,696/year

Senior registered nurse or team lead

At this level, base salary matters less than total compensation. Equity, bonuses, and leadership opportunities in Des Moines's market can add 30-50% to your effective pay.

Registered Nurse Salary Cost Trends in Des Moines

The cost trajectory for registered nurse salary in Des Moines reflects broader trends shaping the midwestern United States. At a cost index of 89, Des Moines has maintained relatively stable pricing, benefiting from a balanced job market where supply roughly matches demand. For those planning major decisions around registered nurse salary in Des Moines, the data suggests taking your time — the market is stable enough to allow careful comparison shopping.

The Bottom Line

Here's what matters for registered nurse salary in Des Moines: at a cost index of 89, this affordable market offers compensation that may seem lower than coastal cities, but your dollar stretches further here. Whether you're evaluating a job offer, planning a career move, or just researching, the data on this page gives you a solid foundation for Des Moines-specific decision-making.

Compare Des Moines with Other Cities

See how registered nurse salary costs compare in nearby markets.

vs Cedar Rapidsvs Omahavs St. JosephAll cities for Registered Nurse Salary

Compare Registered Nurse Salary Pay in Nearby Cities

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Frequently Asked Questions

How does Des Moines compare to other midwest cities?

Among midwestern cities in our database, Des Moines ranks as one of the more affordable options for registered nurse salary. Nearby alternatives include Cedar Rapids and Omaha. Use our comparison tool to see exact category-by-category differences.

When is the best time to look for a job in Des Moines?

Flu season (October-March) and summer vacation coverage create the highest demand for per diem and travel nurses. Rates during these windows are 20-40% above baseline. In Des Moines specifically, local demand patterns follow midwestern climate and economic cycles.

What's the most common mistake people make with registered nurse salary in Des Moines?

Comparing salaries without factoring in benefits. Hospital-employed nurses typically receive health insurance, pension contributions, and tuition reimbursement worth $10,000-20,000/year beyond base pay. This applies in any market, but it's especially costly in Des Moines where even small mistakes can erode the savings you'd otherwise enjoy.

What factors affect registered nurse salary pay in Des Moines?

The main drivers are: local talent demand, cost of living (Des Moines's index: 89), Iowa state income tax rates, industry concentration, and remote work availability. Nursing specialty, shift differential, and facility type create a wider range than most people expect. ICU and OR nurses earn 15-25% more than general floor nurses; night shift adds another 10-15%.

How much does registered nurse salary cost in Des Moines?

Based on 2026 data from BLS and Census Bureau surveys, registered nurse salary in Des Moines, IA typically costs between $34,584 and $59,736. The average of $47,160 puts Des Moines 37% below the national average of $75,000.

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